英文名稱: CIAO2A Antigen (Recombinant Protein)
別 名: cytosolic iron-sulfur assembly component 2A; CIA2A; FAM96A
相關(guān)類別: 抗原
儲(chǔ) 存: 冷凍(-20℃)
概 述
Full name: |
cytosolic iron-sulfur assembly component 2A |
Synonyms: |
CIA2A; FAM96A |
Swissprot: |
Q9H5X1 |
Gene Accession: |
BC008865 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227). |