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  • 產(chǎn)品名稱:RHOH抗原(重組蛋白)

  • 產(chǎn)品型號:100ug
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:800
  • 產(chǎn)品庫存:35
  • 產(chǎn)品文檔:
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詳情介紹:

中文名稱: RHOH抗原(重組蛋白)

英文名稱: RHOH Antigen (Recombinant Protein)

別     名: TTF; ARHH

儲     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to a region derived from 1-191 amino acids of human RHOH

技術(shù)規(guī)格

Full name:

ras homolog family member H

Synonyms:

TTF; ARHH

Swissprot:

Q15669

Gene Accession:

BC014261

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.






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