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  • 產(chǎn)品名稱：MASP1 抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
MASP1 抗原（重組蛋白）始終以服務(wù)國內(nèi)先進(jìn)的研究機(jī)構(gòu)和國內(nèi)高校為己任，在不懈的探索和實踐中，長期以來一直注重品牌建設(shè)，始終把抓產(chǎn)品質(zhì)量作為所有工作的重中之重，所生產(chǎn)銷售的各類試劑受到廣大用戶的廣泛認(rèn)可和信賴。有關(guān)的一切操作和事項，都嚴(yán)格依照步驟依據(jù)，為了保護(hù)結(jié)果真實有效，應(yīng)該以英文版說明書為準(zhǔn)。
詳情介紹：



中文名稱： MASP1 抗原（重組蛋白）

英文名稱： MASP1 Antigen (Recombinant Protein)

別     名：  3MC1; MAP1; MASP; RaRF; CRARF; MASP3; MAp44; PRSS5; CRARF1

相關(guān)類別： 抗原

儲     存：  冷凍（-20℃）  

概     述

Fusion protein corresponding to a region derived from 449-699 amino acids of humanMASP1


技術(shù)規(guī)格

Full name:

mannan binding lectin serine peptidase 1

Synonyms:

3MC1; MAP1; MASP; RaRF; CRARF; MASP3; MAp44; PRSS5; CRARF1

Swissprot:

P48740

Gene Accession:

BC106945

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.







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