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  • 產(chǎn)品名稱：兔抗H2AFX (PhosphoSer139)多克隆抗體

  • 產(chǎn)品型號(hào)：100ul
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：1800
  • 產(chǎn)品庫存：60
  • 產(chǎn)品文檔：
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兔抗H2AFX (Phospho-Ser139)多克隆抗體長期為國內(nèi)科研機(jī)構(gòu)、高校和科研人員提供上等產(chǎn)品，在廣大用戶的幫助和支持下，經(jīng)過不懈的努力，已成為國內(nèi)生命科學(xué)領(lǐng)域產(chǎn)品的主要供應(yīng)商之一，在保證產(chǎn)品質(zhì)量的同時(shí)，還配有扎實(shí)的售后技術(shù)咨詢和服務(wù)，歡迎來電咨詢！
詳情介紹：
中文名稱：  兔抗H2AFX (Phospho-Ser139)多克隆抗體   

英文名稱： Anti-H2AFX (Phospho-Ser139) rabbit polyclonal antibody

別      名： H2AX; H2A.X; H2A/X

相關(guān)類別： 一抗

儲(chǔ)      存： 冷凍（-20℃） 避光

宿      主： Rabbit

抗      原： H2AFX (Phospho-Ser139)

反應(yīng)種屬： Human

標(biāo) 記 物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.

Applications:

WB, IF

Name of antibody:

H2AFX (Phospho-Ser139)

Immunogen:

Synthetic peptide of human H2AFX (Phospho-Ser139)

Full name:

H2A histone family, member X (Phospho-Ser139)

Synonyms：

H2AX; H2A.X; H2A/X

SwissProt:

P16104

WB Predicted band size:

15 kDa

WB Positive control:

HT29 cells treated with UV

WB Recommended dilution:

500-1000

IF Positive control:

Hela cells

IF Recommended dilution

100-200





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