英文名稱： Anti-RB1 rabbit polyclonal antibody
別 名： RB transcriptional corepressor 1; RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1
相關類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： RB1
反應種屬： Human, Mouse, Rat
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術規(guī)格
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Background: |
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
RB1 |
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Immunogen: |
Fusion protein of human RB1 |
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Full name: |
RB transcriptional corepressor 1 |
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Synonyms: |
RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1 |
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SwissProt: |
P06400 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human esophagus cancer |
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IHC Recommend dilution: |
50-100 |
