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  • 產(chǎn)品名稱：兔抗RBM4多克隆抗體

  • 產(chǎn)品型號(hào)：100ul
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：1560
  • 產(chǎn)品庫存：60
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兔抗RBM4多克隆抗體有一支專業(yè)化的銷售和技術(shù)服務(wù)團(tuán)隊(duì)，成熟化的專業(yè)性配備實(shí)驗(yàn)室，力求售前、售中、售后專業(yè)、快捷、方便、及時(shí)，經(jīng)營原則是質(zhì)量**，誠信為本，以質(zhì)量是企業(yè)的生命，誠信是經(jīng)營的資本為警醒，嚴(yán)把所售出商品的質(zhì)量關(guān)。
詳情介紹：
中文名稱：兔抗RBM4多克隆抗體  

英文名稱： Anti-RBM4 rabbit polyclonal antibody

別      名： RNA binding motif protein 4; LARK; RBM4A; ZCRB3A; ZCCHC21

相關(guān)類別： 一抗

儲(chǔ)      存： 冷凍（-20℃）

宿      主： Rabbit

抗      原： RBM4

反應(yīng)種屬： Human, Mouse
 
標(biāo) 記 物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA. Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation. Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress. Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions. Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs. Associates with miRNAs during muscle cell differentiation.

Applications:

ELISA, WB

Name of antibody:

RBM4

Immunogen:

Fusion protein of human RBM4

Full name:

RNA binding motif protein 4

Synonyms:

LARK; RBM4A; ZCRB3A; ZCCHC21

SwissProt:

Q9BWF3

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

40 kDa

WB Positive control:

K562 and HepG2 cell lysates

WB Recommended dilution:

500-2000



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