中文名稱: SF3A3 抗原(重組蛋白)
英文名稱: SF3A3 Antigen (Recombinant Protein)
別 名: splicing factor 3a subunit 3; PRP9; PRPF9; SAP61; SF3a60
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述
Fusion protein corresponding to a region derived from 302-501 amino acids of human SF3A3
技術(shù)規(guī)格
Full name:
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splicing factor 3a subunit 3
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Synonyms:
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PRP9; PRPF9; SAP61; SF3a60
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Swissprot:
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Q12874
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Gene Accession:
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BC002395
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Purity:
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>85%, as determined by Coomassie blue stained SDS-PAGE
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Expression system:
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Escherichia coli
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Tags:
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His tag C-Terminus, GST tag N-Terminus
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Background:
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This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.
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