中文名稱: 兔抗MAGEB5多克隆抗體
英文名稱: Anti-MAGEB5 rabbit polyclonal antibody
別 名: CT3.3; MAGE-B5
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: MAGEB5
反應(yīng)種屬: Human
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in ***** tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B5 (melanoma-associated antigen B5), also known as CT3.3 (cancer/testis antigen 3.3), is a 275 amino acid protein that contains one MAGE domain and is expressed in testis. The gene encoding MAGE-B5 maps to human chromosome X, which consists of about 153 million base pairs and nearly 1,000 genes. Color blindness, hemophilia and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently, as males carry a single X chromosome. |
Applications: |
ELISA, IHC |
Name of antibody: |
MAGEB5 |
Immunogen: |
Synthetic peptide of human MAGEB5 |
Full name: |
MAGE family member B5 |
Synonyms: |
CT3.3; MAGE-B5 |
SwissProt: |
Q9BZ81 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human thyroid cancer and human liver cancer |
IHC Recommend dilution: |
20-100 |