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  • 產(chǎn)品名稱： 兔抗MAPK8多克隆抗體

  • 產(chǎn)品型號(hào)：100ul
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：1560
  • 產(chǎn)品庫(kù)存：60
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中文名稱：  兔抗MAPK8多克隆抗體    

英文名稱： Anti-MAPK8 rabbit polyclonal antibody

別      名： JNK, JNK1, PRKM8, SAPK1, JNK-46, JNK1A2, SAPK1c, JNK21B1/2

抗      原： MAPK8

儲(chǔ)      存： 冷凍（-20℃）

宿      主： Rabbit

相關(guān)類(lèi)別： 一抗

反應(yīng)種屬： Human, Mouse, Rat

標(biāo) 記 物： Unconjugate

克隆類(lèi)型： rabbit polyclonal

技術(shù)規(guī)格

Background:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

Applications:

ELISA, WB, IHC

Name of antibody:

MAPK8

Immunogen:

Fusion protein of human MAPK8

Full name:

mitogen-activated protein kinase 8

Synonyms:

JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2

SwissProt:

P45983

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human prostate cancer and Human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

48 kDa

WB Positive control:

Jurkat, K562, Hela, A172 cell, Mouse brain tissue lysates

WB Recommended dilution:

500-2000




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