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  • 產(chǎn)品名稱:兔抗MAPK10多克隆抗體

  • 產(chǎn)品型號:100ul
  • 產(chǎn)品廠商:通蔚生物
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中文名稱:  兔抗MAPK10多克隆抗體   

英文名稱: Anti-MAPK10 rabbit polyclonal antibody

別    名: JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK

相關(guān)類別: 一抗

儲    存: 冷凍(-20℃)

宿    主: Rabbit

抗    原: MAPK10

反應(yīng)種屬: Human, Mouse, Rat

標 記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Applications:

ELISA, WB, IHC

Name of antibody:

MAPK10

Immunogen:

Synthetic peptide of human MAPK10

Full name:

mitogen-activated protein kinase 10

Synonyms:

JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK

SwissProt:

P53779

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human breast cancer

IHC Recommend dilution:

5-20

WB Predicted band size:

53 kDa

WB Positive control:

293T cells

WB Recommended dilution:

500-2000





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