中文名稱(chēng): 兔抗MBP多克隆抗體
英文名稱(chēng): Anti-MBP rabbit polyclonal antibody
別 名: MGC99675
相關(guān)類(lèi)別: 一抗
儲(chǔ) 存: 冷凍(-20℃) 避光
宿 主: Rabbit
抗 原: MBP
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類(lèi)型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation. |
Applications: |
WB |
Name of antibody: |
MBP |
Immunogen: |
Synthetic peptide of human MBP |
Full name: |
myelin basic protein |
Synonyms: |
MGC99675 |
SwissProt: |
P02686 |
WB Predicted band size: |
33 kDa |
WB Positive control: |
Rat brain, Mouse brain and Rat hippocampus Tissue |
WB Recommended dilution: |
500-1000 |