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  • 產(chǎn)品名稱:LRRC19 抗原(重組蛋白)

  • 產(chǎn)品型號:1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:3580
  • 產(chǎn)品庫存:35
  • 產(chǎn)品文檔:
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簡單介紹:
LRRC19 抗原(重組蛋白)始終以服務國內(nèi)先進的研究機構(gòu)和國內(nèi)高校為己任,在不懈的探索和實踐中,長期以來一直注重品牌建設,始終把抓產(chǎn)品質(zhì)量作為所有工作的重中之重,所生產(chǎn)銷售的各類試劑受到廣大用戶的廣泛認可和信賴。有關的一切操作和事項,都嚴格依照步驟依據(jù),為了保護結(jié)果真實有效,應該以英文版說明書為準。
詳情介紹:



中文名稱: LRRC19 抗原(重組蛋白)

英文名稱: LRRC19 Antigen (Recombinant Protein)

別     名:  leucine rich repeat containing 19

相關類別: 抗原

儲     存:  冷凍(-20℃) 

概     述

Fusion protein corresponding to a region derived from 171-370 amino acids of human LRRC19

技術(shù)規(guī)格

Full name:

leucine rich repeat containing 19

Swissprot:

Q9H756

Gene Accession:

BC126156

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappaB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.







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