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  • 產(chǎn)品名稱：PHF21A 抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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PHF21A 抗原（重組蛋白）一直以來，以誠信為基礎(chǔ)，以質(zhì)量為保證，使得公司一直保持穩(wěn)健的發(fā)展，目前，客戶主要分布在生物生產(chǎn)及科研領(lǐng)域，我們珍視您的長期信賴和支持，今后將一如既往地把上等的服務(wù)帶給客戶、和客戶分享*新的科技資訊，為創(chuàng)造更加美好的生活而努力。
詳情介紹：


中文名稱： PHF21A 抗原（重組蛋白）

英文名稱： PHF21A Antigen (Recombinant Protein)

別     名：  PHD finger protein 21A; BHC80; BM-006

相關(guān)類別： 抗原

儲     存：  冷凍（-20℃）

概     述

Fusion protein corresponding to a region derived from 481-680 amino acids of human PHF21A

技術(shù)規(guī)格

Full name:

PHD finger protein 21A

Synonyms:

BHC80; BM-006

Swissprot:

Q96BD5

Gene Accession:

BC015714

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A (PHD finger protein 21A), also known as BRAF35-HDAC complex protein BHC80, is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.





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