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  • 產(chǎn)品名稱:PGRMC2 抗原(重組蛋白)

  • 產(chǎn)品型號(hào):100ug
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價(jià)格:800
  • 產(chǎn)品庫(kù)存:35
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中文名稱: PGRMC2 抗原(重組蛋白)

英文名稱: PGRMC2 Antigen (Recombinant Protein)

別     名:  progesterone receptor membrane component 2; DG6; PMBP

儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to a region derived from 101-223 amino acids of human PGRMC2

技術(shù)規(guī)格

Full name:

progesterone receptor membrane component 2

Synonyms:

DG6; PMBP

Swissprot:

O15173

Gene Accession:

BC016692

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas.







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